Antibiotic prescriptions associated with a diagnosis of acute nasopharyngitis by general GPs in France: a retrospective study
2024

Antibiotic Prescriptions for Nasopharyngitis in France

Sample size: 754476 publication Evidence: high

Author Information

Author(s): Duong Tran Tue, Matta Matta, Lekens Beranger, Diamantis Sylvain

Primary Institution: Service de Maladies Infectieuses et Tropicales, Centre Hospitalier de Melun, Melun, France

Hypothesis

What are the characteristics of antibiotic prescriptions for patients with acute nasopharyngitis by general practitioners in France?

Conclusion

Antibiotics are frequently over-prescribed for nasopharyngitis, with a prescription rate of 16%.

Supporting Evidence

  • Antibiotics were prescribed in 16.1% of cases over the 4 years covered by this study.
  • Amoxicillin was the most prescribed antibiotic, accounting for 59.5% of all antibiotic prescriptions.
  • Older GPs prescribed more antibiotics than younger GPs.
  • 78.8% of prescribed medications were either not recommended or contraindicated according to national guidelines.

Takeaway

Doctors in France often give antibiotics for a common cold, even though they usually don't help. This study looked at how often this happens.

Methodology

Retrospective analysis of prescription data from 2637 GPs over four years.

Potential Biases

Possible bias due to reliance on GPs' clinical assessments without microbiological confirmation.

Limitations

The study could not access complete records, leading to potential diagnostic classification bias.

Participant Demographics

The study included 2637 GPs, with a median age of 60 years, and 754476 patients, with a median age of 23 years.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI = 15.93 to 16.07

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3399/BJGPO.2024.0006

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