West Nile Virus and Pregnancy: A Systematic Review
Author Information
Author(s): Marnezi Maria, Tsiakalos Aristotelis, Akinosoglou Karolina
Primary Institution: Hellenic Open University
Hypothesis
What is the impact of West Nile Virus on pregnancy and neonatal outcomes?
Conclusion
West Nile Virus infection is mostly associated with favorable outcomes during pregnancy, but larger cohorts are needed to confirm these findings.
Supporting Evidence
- Fever was the most common symptom among pregnant women with WNV.
- Most neonates had normal Apgar scores and developmental functions.
- Antibodies against WNV were found in breast milk, but no transmission to neonates was observed.
Takeaway
This study looked at how West Nile Virus affects pregnant women and their babies, finding that most pregnancies go well even if the mother gets the virus.
Methodology
A systematic review of primary studies from PUBMED, SCOPUS, Google, and Google Scholar, following PRISMA guidelines.
Potential Biases
Potential publication bias and variability in study designs and populations.
Limitations
Publication bias, quality of primary studies, heterogeneity among populations, and limited data available.
Participant Demographics
Pregnant women with West Nile Virus infection, primarily from studies conducted in the USA.
Digital Object Identifier (DOI)
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