Double vs single internal thoracic artery harvesting in diabetic patients: role in perioperative infection rate
2008

Double vs Single Internal Thoracic Artery Harvesting in Diabetic Patients

Sample size: 81 publication Evidence: moderate

Author Information

Author(s): Marco Agrifoglio, Matteo Trezzi, Fabio Barili, Luca Dainese, Faisal H Cheema, Veli K Topkara, Chiara Ghislandi, Alessandro Parolari, Gianluca Polvani, Francesco Alamanni, Paolo Biglioli

Primary Institution: Centro Cardiologico Monzino, University of Milan

Hypothesis

Does bilateral internal thoracic artery harvesting increase the risk of surgical site infections in diabetic patients with poor glycemic control?

Conclusion

CABG with bilateral pedicled ITAs grafting could be performed safely even in diabetics with poor preoperative glycaemic control.

Supporting Evidence

  • Five patients developed sternal SSIs, with no significant difference between the two groups.
  • The overall survival estimate at 1 year was 98.7%.
  • Only BMI was a significant predictor of SSI.

Takeaway

The study looked at whether using two arteries instead of one during heart surgery is safe for diabetic patients. It found that using two arteries doesn't increase the risk of infections.

Methodology

This prospective study involved 81 diabetic patients undergoing elective CABG, comparing outcomes between those receiving single and double internal thoracic artery harvesting.

Potential Biases

Potential confounding factors due to non-randomization.

Limitations

The study was not randomized and had a limited sample size.

Participant Demographics

Patients were diabetic with uncontrolled glycemia, aged between 62 and 66.5 years, with a majority being male.

Statistical Information

P-Value

0.04

Confidence Interval

1.02–1.83

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1749-8090-3-35

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