Platelet-Rich Plasma Versus Corticosteroid Injections for Chronic Tendinopathies: A Systematic Review and Meta-Analysis
2024

Comparing Platelet-Rich Plasma and Corticosteroid Injections for Chronic Tendinopathies

Sample size: 918 publication 10 minutes Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Elnewishy Ahmed, Elsenosy Abdelfatah M, Teama Hagar, Symeon Naoum, Hamada Ahmed

Hypothesis

This review aims to compare the effectiveness of PRP and corticosteroid injections for chronic tendinopathies regarding pain reduction and functional improvement.

Conclusion

Both PRP and corticosteroid injections provide comparable short-term pain relief, but PRP may offer limited long-term benefits in functional outcomes.

Supporting Evidence

  • PRP and CS injections showed no significant difference in short-term pain reduction.
  • Functional outcomes were comparable in the short term but showed a trend favoring PRP at longer follow-up periods.
  • PRP exhibited a slight advantage in long-term functional recovery, though results were not statistically significant.

Takeaway

Doctors are trying to find out if a special treatment using platelets from your blood works better than regular steroid shots for helping sore tendons feel better.

Methodology

A systematic review and meta-analysis of randomized controlled trials comparing PRP and corticosteroid injections for chronic tendinopathies.

Potential Biases

Some studies exhibited concerns in areas such as missing outcome data and outcome measurement.

Limitations

Many studies had small sample sizes, were unblinded, or had limited follow-up periods, and there was significant heterogeneity in PRP preparation techniques.

Participant Demographics

The mean age ranged from 41.85 to 57.33 years, with female representation varying from 19% to 81%.

Statistical Information

P-Value

0.95

Confidence Interval

95% CI: -0.64 to 0.88

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7759/cureus.76051

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