Critical appraisal and narrative review of the literature in IVF/ICSI patients with adenomyosis and endometriosis
2024
Impact of Adenomyosis and Endometriosis on IVF Outcomes
publication
Evidence: moderate
Author Information
Author(s): Mercan Ramazan, Benlioglu Can, Aksakal Gulumser Ece
Primary Institution: Koc University, İstanbul, Türkiye
Hypothesis
How do adenomyosis and endometriosis affect assisted reproductive technology outcomes?
Conclusion
Adenomyosis negatively impacts assisted reproductive technology outcomes, particularly increasing miscarriage rates.
Supporting Evidence
- Endometriosis and adenomyosis often coexist, complicating infertility.
- Studies show that while endometriosis may not significantly impact IVF outcomes, adenomyosis is associated with higher miscarriage rates.
- Ultralong GnRH agonist protocols may help improve outcomes in patients with adenomyosis.
Takeaway
Adenomyosis and endometriosis can make it harder for women to get pregnant, especially when they occur together.
Methodology
The study critically appraises existing literature, focusing on meta-analyses and large cohort studies.
Limitations
The study highlights the need for more research to clarify the complex interactions between adenomyosis, endometriosis, and ART outcomes.
Digital Object Identifier (DOI)
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