Cholesterol lowering effect of a soy drink enriched with plant sterols in a French population with moderate hypercholesterolemia
2008

Cholesterol Lowering Effect of a Soy Drink with Plant Sterols

Sample size: 50 publication Evidence: moderate

Author Information

Author(s): Christina Weidner, Michel Krempf, Jean-Marie Bard, Murielle Cazaubiel, Doris Bell

Primary Institution: Cognis GmbH, Monheim, Germany

Hypothesis

Does a soy drink enriched with plant sterols effectively lower cholesterol levels in individuals with moderate hypercholesterolemia?

Conclusion

Daily consumption of a plant sterol-enriched soy drink significantly decreased total, non-HDL, and LDL cholesterol.

Supporting Evidence

  • LDL-C was reduced by 0.29 mmol/l or 7% compared to baseline.
  • Total cholesterol decreased by 0.26 mmol/l.
  • Non-HDL-C concentrations decreased by 0.31 mmol/l.
  • Compliance was very high (>96%).
  • The control group did not show significant changes in blood lipids.

Takeaway

Drinking a special soy milk with added plant stuff can help lower bad cholesterol in people with high cholesterol.

Methodology

A randomized, placebo-controlled double-blind study with 50 subjects consuming either a soy drink with or without plant sterols for 8 weeks.

Potential Biases

Potential bias due to self-reported compliance and satisfaction.

Limitations

The study was limited to a specific population and the effects of soy protein alone were not assessed.

Participant Demographics

50 subjects (19 men, 31 women) aged 19 to 65 years with moderate hypercholesterolemia.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-511X-7-35

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