Impact of Universal Varicella Vaccination in Uruguay
Author Information
Author(s): J Quian, R Rüttimann, C Romero, P Dall’Orso, A Cerisola, T Breuer, M Greenberg, T Verstraeten
Primary Institution: Republic University, Montevideo, Uruguay
Hypothesis
The introduction of universal varicella vaccination in Uruguay will significantly reduce hospitalizations and outpatient visits for varicella among children.
Conclusion
The burden of varicella has decreased substantially in Uruguayan children since the introduction of the varicella vaccination.
Supporting Evidence
- Hospitalizations due to varicella reduced by 81% overall.
- Ambulatory visits for varicella decreased by 87% overall.
- Significant reductions were observed in all age groups studied.
Takeaway
After starting the varicella vaccine program, fewer kids got sick and had to go to the hospital for chickenpox.
Methodology
Data on hospitalizations and medical consultations for varicella were collected from health systems in Montevideo and compared before and after vaccination.
Potential Biases
Potential under-reporting of cases in one health system could affect findings.
Limitations
The study could not confirm reported varicella cases by laboratory testing and may have overestimated the impact of vaccination.
Participant Demographics
The study focused on children under 15 years old in Montevideo, Uruguay.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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