Plasma iFGF23 Levels in Women with Bulimia Nervosa
Author Information
Author(s): Otani Makoto, Takimoto Yoshiyuki, Moriya Junko, Yoshiuchi Kazuhiro, Akabayashi Akira
Primary Institution: The University of Tokyo
Hypothesis
This study aims to determine plasma iFGF23 concentrations in bulimia nervosa patients and healthy controls.
Conclusion
Bulimia nervosa patients have elevated plasma iFGF23 levels, especially those with a high frequency of binge eating.
Supporting Evidence
- Median plasma iFGF23 levels were greater in BN patients than in controls.
- BN patients with high frequency of binge eating had the highest plasma iFGF23 levels.
- There were no significant differences in plasma calcium, phosphate, or vitamin D levels among the groups.
Takeaway
Women with bulimia nervosa have higher levels of a certain protein in their blood, which might help show how often they binge eat.
Methodology
The study measured plasma iFGF23 levels in 13 bulimia nervosa patients and 11 healthy controls using an ELISA kit.
Limitations
The small sample size and lack of data on binge eating volume and dietary phosphate intake.
Participant Demographics
13 female bulimia nervosa patients and 11 healthy female controls.
Statistical Information
P-Value
p = 0.002
Confidence Interval
35.5 [14.8-65.0] pg/ml for BN patients; 3.8 [not detected-5.3] pg/ml for controls
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website