Methyl 4-hydroxy-2-isopropyl-1,1-dioxo-2H-1,2-benzothiazine-3-carboxylate
2011

Crystal Structure of a Benzothiazine Derivative

publication Evidence: moderate

Author Information

Author(s): Arshad Muhammad Nadeem, Khan Islam Ullah, Zia-ur-Rehman Muhammad, Rafique H. M., Holman K. Travis

Primary Institution: University of the Punjab

Conclusion

The study reveals the crystal structure of a benzothiazine derivative, highlighting its unique molecular conformation and hydrogen bonding interactions.

Supporting Evidence

  • The crystal structure shows maximum deviations of S and N atoms from the least-squares plane.
  • The thiazine ring adopts a half chair conformation.
  • Intramolecular and intermolecular hydrogen bonding interactions were observed.

Takeaway

Scientists studied a special molecule and found out how it is shaped and how its parts stick together, which is important for making medicines.

Methodology

The crystal structure was analyzed using X-ray diffraction techniques.

Digital Object Identifier (DOI)

10.1107/S1600536811024573

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