Promotora intervention for metabolic and mental health to reduce type 2 diabetes risk: a pilot randomized controlled trial
2024

Promotora Intervention for Metabolic and Mental Health to Reduce Type 2 Diabetes Risk

Sample size: 40 publication 10 minutes Evidence: moderate

Author Information

Author(s): Vargas Maria C., Katz Joshua B., Lopez Azucena, Carrillo Arturo, Gregory Dyanna L., O’Brien Matthew J.

Primary Institution: Northwestern University Feinberg School of Medicine

Hypothesis

Can a novel behavioral intervention (PRIME2) effectively reduce diabetes risk and perceived stress among Spanish-speaking Latinx adults with prediabetes?

Conclusion

The PRIME2 intervention led to significant weight loss but did not significantly reduce perceived stress compared to usual care.

Supporting Evidence

  • PRIME2 participants lost an average of 3.7 lbs compared to usual care.
  • 95% of participants were women, with a mean age of 49.9 years.
  • Participants had a mean BMI of 33.3 kg/m2 and elevated HbA1c levels.

Takeaway

This study tested a program to help people lose weight and feel less stressed, and it worked for weight loss but not for stress.

Methodology

A pilot randomized controlled trial comparing the PRIME2 intervention to usual care over 16 sessions.

Potential Biases

The majority of participants were women, which may limit the generalizability of the findings.

Limitations

The study had a small sample size and did not require participants to have elevated stress levels at baseline.

Participant Demographics

Participants were primarily middle-aged Spanish-speaking Latinx women with prediabetes.

Statistical Information

P-Value

0.02

Confidence Interval

[-6.8, -0.7]

Statistical Significance

p=0.02

Digital Object Identifier (DOI)

10.1038/s41598-024-83482-5

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