Calcium Hydroxide vs. Double Antibiotic Paste in Endodontic Treatment
Author Information
Author(s): Afsaneh Rahmati, Seyedein Farshad, Omid Dianat, Sara Saedi, Golriz Rostami, Alireza Akbarzadeh Baghban, Shima Sabertahan, Majid Kazem
Primary Institution: Shahid Beheshti University of Medical Sciences
Hypothesis
The study aims to compare the efficacy of double antibiotic paste (DAP) and calcium hydroxide (CH) in treating teeth with large periapical lesions.
Conclusion
The DAP group showed significantly better outcomes compared to the CH group in treating teeth with periapical lesions.
Supporting Evidence
- At the 12-month follow-up, 40% of cases in the DAP group were healed, while none in the CH group were completely healed.
- The study used a triple-blind design to minimize bias.
- The sample size was calculated to ensure adequate power for the statistical analysis.
Takeaway
This study found that using double antibiotic paste helps heal infected teeth better than calcium hydroxide.
Methodology
Thirty maxillary anterior teeth with necrotic pulps and apical periodontitis were randomly assigned to receive either CH or DAP as intracanal medicaments, followed by clinical and radiographic assessments at 6 and 12 months.
Potential Biases
The study was conducted at a single center, which may limit the generalizability of the findings.
Limitations
The study had a short follow-up period and relied on digital radiography, which may not be as accurate as advanced imaging techniques like CBCT.
Participant Demographics
Participants were 30 patients aged 18 to 30 years with nonvital anterior maxillary teeth and apical periodontitis.
Statistical Information
P-Value
0.017
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website