Comparative and Functional Genomics
2003
Yeast Transcriptome and E. coli Mutants
publication
Author Information
Author(s): Becerra, Kaderbhai, Rita Casadio, Xin Yuan, Anna Tramontano, Pier Luigi Martelli, Patrick Aloy, Robert Russell, Fabrizio Ferré, Rachel Bell, Nir Ben-Tal, Alfonso Valencia, Susan Jones, Janet Thornton, Naomi Siew, Daniel Fischer, Silvia Saviozzi, Raffaele Calogero
Conclusion
The study successfully discriminated E. coli mutants based on their metabolic profiles.
Supporting Evidence
- The yeast transcriptome was analyzed under different temperature shocks.
- E. coli mutants were differentiated based on their metabolic outputs.
Takeaway
Scientists looked at how yeast reacts to heat and cold, and also figured out how to tell different E. coli mutants apart by what they release into their surroundings.
Methodology
The study involved exposing yeast cells to heat and cold shocks and analyzing gene expression changes, as well as using metabolic footprinting for E. coli mutants.
Digital Object Identifier (DOI)
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