Prevalence and Risk Factors for Atherosclerotic Cardiovascular Disease in 7704 Individuals: An Analysis from the Greek Registry for the Prevalence of Familial Hypercholesterolemia (GRegistry-FH)
2024

Prevalence and Risk Factors for Atherosclerotic Cardiovascular Disease in Greece

Sample size: 7704 publication Evidence: high

Author Information

Author(s): Kolovou Genovefa, Makrygiannis Stamatis, Marvaki Christina, Pavlatou Niki, Anagnostopoulou Katerina, Giannakopoulou Vasiliki, Goumas Georgios, Kalogeropoulos Petros, Kolovou Vana, Limberi Sotiria, Perrea Despina, Tzenalis Anastasios, Emre Zeimpek, Jahaj Edison, Kasiara Zoi, Giannakoulis Ilias, Tsolakoglou Ioannis, Kadda Olga, Tsaloukidis Nikolaos, Koulaxidou Rafailia, Marvaki Aikaterini, Foussas Stefanos, Melidonis Andreas, Hoursalas Giannis, Vlachopoulos Charalambos, Katsiki Niki, Milionis Haralampos, Liberopoulos Evaggelos, Bilianou Helen, Puddu Paolo Emilio

Primary Institution: Hellenic College of Treatment of Atherosclerosis

Hypothesis

What is the prevalence of atherosclerotic cardiovascular disease (ASCVD) and its risk factors among individuals in Greece?

Conclusion

The study found a significant prevalence of ASCVD and its risk factors among Greek adults, indicating a need for early detection and management strategies.

Supporting Evidence

  • The prevalence of ASCVD was found to be 13.9%.
  • Treated hypercholesterolemia was present in 20.1% of participants.
  • 24% of individuals had arterial hypertension.
  • 11.3% of participants had diabetes mellitus.
  • 37.9% of participants were smokers.
  • 60.5% reported a family history of ASCVD.
  • 25.5% of participants had pre-diabetes.

Takeaway

This study looked at a lot of people in Greece to see how many have heart problems and what causes them. They found many people have these issues, so it's important to catch them early.

Methodology

The study used door-to-door interviews conducted by trained interviewers to collect data from a randomly selected cohort across Greece.

Potential Biases

Self-reported data for ASCVD risk factors may lead to inaccuracies, although biochemical data were also reviewed to minimize bias.

Limitations

The study's cross-sectional design may not capture temporal changes in prevalence, and self-reported data may introduce recall bias.

Participant Demographics

Participants were aged 18 years and older, with a gender distribution of 3262 men and 4442 women.

Digital Object Identifier (DOI)

10.3390/jcdd11120411

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