Are the distributions of variations of circle of Willis different in different populations? – Results of an anatomical study and review of literature
2006

Variations of the Circle of Willis in Different Populations

Sample size: 102 publication Evidence: moderate

Author Information

Author(s): Eftekhar Behzad, Dadmehr Majid, Ansari Saeed, Ghodsi Mohammad, Nazparvar Bashir, Ketabchi Ebrahim

Primary Institution: Sina Trauma and Surgery Research Center and Department of Neurosurgery, Sina Hospital, Tehran University, Tehran, Iran

Hypothesis

Do the distributions of variations of the circle of Willis differ in different populations?

Conclusion

The anatomical variations found in the cerebral arterial circle of Iranian males were not significantly different from those of more diverse populations reported in the literature.

Supporting Evidence

  • Variants with uni- and bilateral hypoplasia of posterior communicating arteries were the most common in the study.
  • No hypoplasia of the precommunicating part of the left anterior cerebral artery (A1) was seen.
  • In 3% of cases, both right and left posterior communicating arteries were absent.

Takeaway

The study looked at the brain arteries of 102 Iranian men to see if their variations were different from those in other populations, and found they were quite similar.

Methodology

Dissection of 102 brains of recently deceased Iranian males to observe variations in the anatomy of the cerebral arterial circle.

Potential Biases

The study only included male subjects, which may limit the generalizability of the findings.

Limitations

Potential changes in vessel diameter over time and reliance on postmortem measurements may affect the accuracy of results.

Participant Demographics

102 recently deceased Iranian males aged between 15 and 75 years (mean age 38 ± 15 years).

Digital Object Identifier (DOI)

10.1186/1471-2377-6-22

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