Milk-Derived Extracellular Vesicles: Isolation, Characterization, and Functions
Author Information
Author(s): Di Shujuan, Huang Yibo, Qiao Weicang, Zhang Xiaomei, Wang Yaling, Zhang Minghui, Fu Jieyu, Zhao Junying, Chen Lijun
Primary Institution: Beijing Sanyuan Foods Co. Ltd.
Hypothesis
Milk-derived extracellular vesicles (EVs) have various functions, including immune regulation and promoting intestinal development.
Conclusion
Milk-derived EVs have substantial potential for application in infant formula and functional foods development.
Supporting Evidence
- Milk-derived EVs carry proteins, lipids, and nucleic acids away from their parental cells, acting as messengers between cells.
- Breast milk is a rich source of EVs, which are critical for the immune system and neurodevelopment of infants.
- Milk-derived EVs have been shown to improve intestinal function and prevent inflammation.
Takeaway
Milk from cows and other mammals contains tiny bubbles called extracellular vesicles that help babies grow and stay healthy.
Methodology
This review summarizes the isolation and characterization methods for milk-derived EVs and their biological functions and roles.
Limitations
The extraction technology of EVs still needs to be improved, and existing methods have specific drawbacks in isolation efficiency and reproducibility.
Digital Object Identifier (DOI)
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