No effect of an oleoylethanolamide-related phospholipid on satiety and energy intake: a randomised controlled trial of phosphatidylethanolamine
2008

Effect of Phosphatidylethanolamine on Hunger and Eating

Sample size: 18 publication Evidence: moderate

Author Information

Author(s): Fiona Lithander, C. Strik, A-T. McGill, A.K. MacGibbon, B.H. McArdle, S.D. Poppitt

Primary Institution: University of Auckland, New Zealand

Hypothesis

Can phosphatidylethanolamine-containing lipids inhibit food intake and enhance satiety?

Conclusion

The study found no evidence that dietary phospholipids containing phosphatidylethanolamine can modify eating behavior.

Supporting Evidence

  • Participants reported lower hunger and higher fullness after consuming the lipid treatments compared to water control.
  • Energy intake was lower after the lipid treatments compared to the water control.
  • No significant differences in hunger and fullness were found between the phosphatidylethanolamine treatments and the no-PE control.

Takeaway

The study tested if a type of fat could help people feel less hungry, but it didn't work as expected.

Methodology

Eighteen male participants were given different types of high-fat breakfasts containing varying levels of phosphatidylethanolamine, and their hunger and energy intake were measured.

Limitations

The study was short-term and only included lean males, which may limit the generalizability of the findings.

Participant Demographics

Eighteen healthy, non-smoking male adults aged around 25 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-511X-7-41

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