Survey on Referrals to Phase I Oncology Trials
Author Information
Author(s): Brunetto Andre, Olmos David, Arkenau Hendrik-Tobias, Tan Daniel, Yap Timomy, de Bono Johann, Barriuso Jorge, Kaye Stan
Primary Institution: The Royal Marsden Hospital
Hypothesis
What are the referral patterns and perceptions of oncologists regarding Phase I oncology trials?
Conclusion
Improving communication with referring oncologists can enhance patient selection for Phase I oncology trials.
Supporting Evidence
- 64% of oncologists responded to the survey.
- 31% referred patients due to lack of treatment options.
- 93% assessed performance status before referral.
- 47% of oncologists would change their referral approach after reviewing outcome data.
Takeaway
Doctors were asked about why they send patients to experimental cancer treatments, and many said they would change how they refer patients after learning more about the results of these treatments.
Methodology
A structured questionnaire was sent to referring oncologists to assess their perceptions and referral patterns before and after reviewing clinical outcome data.
Potential Biases
Potential bias due to self-reported data from oncologists.
Limitations
The survey may have limitations in capturing all factors influencing referral decisions.
Participant Demographics
Medical and clinical oncologists with varying years of experience.
Statistical Information
P-Value
0.029
Confidence Interval
95% CI 41.3–53.6
Statistical Significance
p=0.029
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website