Mutacin H-29B is identical to mutacin II (J-T8)
2006
Characterization of Mutacin H-29B from Streptococcus mutans
publication
Evidence: moderate
Author Information
Author(s): Nicolas Guillaume, Morency Hélène, LaPointe Gisèle, Lavoie Marc C
Primary Institution: Université Laval
Hypothesis
The study aims to produce and characterize a new mutacin from S. mutans strain 29B.
Conclusion
Mutacin H-29B is identical to mutacin II (J-T8) over the first 24 amino acids, indicating that S. mutans strains can produce similar bacteriocins.
Supporting Evidence
- Mutacin H-29B was purified from a liquid preparation consisting of cheese whey permeate and yeast extract.
- The amino acid sequence of mutacin H-29B was found to be identical to mutacin II (J-T8) over the first 24 residues.
- The molecular mass of mutacin H-29B was evaluated at 3246.08 ± 0.1 Da.
Takeaway
Scientists found a new substance made by bacteria that can kill other germs, and it turns out it's the same as one they already knew about.
Methodology
Mutacin H-29B was purified using hydrophobic chromatography from a liquid culture medium.
Digital Object Identifier (DOI)
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