A Rare Cause of Fatty Liver and Elevated Aminotransferase Levels: Chanarin-Dorfman Syndrome: A Case Report
2011

Chanarin-Dorfman Syndrome: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Ersoy Özdal, Alkım Canan, Onuk Mehmet Derya, Demirsoy Hüseyin, Argon Dilek

Primary Institution: Şişli Etfal Training and Research Hospital, Istanbul, Turkey

Conclusion

The case highlights the importance of recognizing Chanarin-Dorfman syndrome to avoid unnecessary investigations in patients with ichthyosis.

Supporting Evidence

  • Chanarin-Dorfman syndrome is a rare inherited disorder characterized by ichthyosis and liver involvement.
  • The patient presented with elevated transaminases and hepatosteatosis.
  • Awareness of this syndrome can lead to prompt diagnosis and avoid unnecessary investigations.

Takeaway

This study talks about a rare condition called Chanarin-Dorfman syndrome that can cause skin problems and liver issues. A simple blood test can help doctors find it early.

Methodology

The diagnosis was made through clinical examination, blood tests, and liver biopsy.

Limitations

The study is based on a single case report, limiting the generalizability of the findings.

Participant Demographics

A 20-year-old Turkish woman born to consanguineous parents.

Digital Object Identifier (DOI)

10.4061/2011/341372

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