Does improving maternal knowledge of vaccines impact infant immunization rates? A community-based randomized-controlled trial in Karachi, Pakistan
2011

Impact of Maternal Education on Infant Vaccination Rates

Sample size: 366 publication 10 minutes Evidence: high

Author Information

Author(s): Owais Aatekah, Hanif Beenish, Siddiqui Amna R, Agha Ajmal, Zaidi Anita KM

Primary Institution: Aga Khan University

Hypothesis

Does improving maternal knowledge of vaccines impact infant immunization rates?

Conclusion

A simple educational intervention designed for low-literate populations improved DPT-3/Hepatitis B vaccine completion rates by 39%.

Supporting Evidence

  • 129 (72.1%) infants in the intervention group received all 3 doses of DPT/Hepatitis B vaccine.
  • 92 (51.7%) infants in the control group received all 3 doses.
  • The intervention improved DPT-3/Hepatitis B immunization rates by 39%.
  • Vaccination cards were retained by 81% of participants in the intervention group.

Takeaway

Teaching mothers about vaccines helps more babies get their shots.

Methodology

Randomized controlled trial with 366 mother-infant pairs receiving either an educational intervention or general health promotion messages.

Potential Biases

Potential misclassification bias due to reliance on vaccination cards for proof of immunization.

Limitations

High refusal rate (27%) and lack of blinding for participants and CHWs.

Participant Demographics

Mothers living in low-income, low-literacy communities in Karachi, Pakistan.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 1.06-1.81

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2458-11-239

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