Reported analgesic administration to rabbits undergoing experimental surgical procedures
2011

Analgesic Use in Rabbits During Surgery

Sample size: 128 publication Evidence: moderate

Author Information

Author(s): Coulter Claire A, Flecknell Paul A, Leach Matthew C, Richardson Claire A

Primary Institution: Comparative Biology Centre, Newcastle University, Newcastle upon Tyne, UK

Hypothesis

Is the administration of systemic analgesics to rabbits undergoing surgical procedures increasing over time?

Conclusion

The study found that while the reporting of systemic analgesic administration to rabbits is increasing, not all rabbits undergoing surgery receive adequate pain relief.

Supporting Evidence

  • The percentage of papers reporting systemic analgesia increased from 16% to 50% between 1995-1997 and 2005-2007.
  • Papers that reported ethical approval were more likely to report systemic analgesic administration.
  • Buprenorphine was the most frequently used analgesic in both time periods.

Takeaway

This study looked at how often rabbits get pain medicine during surgery. It found that more rabbits are getting pain relief now than before, but many still don't get any.

Methodology

A structured literature review of 128 papers from 51 peer-reviewed journals was conducted to assess trends in analgesic administration to rabbits.

Potential Biases

Potential bias in reporting due to the reliance on published literature, which may not fully capture actual practices.

Limitations

The study only reviewed published papers, which may not represent all practices in rabbit analgesia.

Participant Demographics

The majority of studies reported using male rabbits more frequently than females.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1746-6148-7-12

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