High prevalence of lung cancer in a surgical cohort of lung cancer patients a decade after smoking cessation
2011

High Prevalence of Lung Cancer in Former Smokers

Sample size: 626 publication Evidence: moderate

Author Information

Author(s): Mong Cindy, Garon Edward B, Fuller Clark, Mahtabifard Ali, Mirocha James, Mosenifar Zab, McKenna Robert

Primary Institution: Cedars Sinai Medical Center

Hypothesis

What is the prevalence of smoking at the time of lung cancer diagnosis in a surgical patient cohort?

Conclusion

Most lung cancer patients in this surgical cohort had stopped smoking more than a decade before their diagnosis.

Supporting Evidence

  • 77% of patients had a smoking history.
  • 11.3% of patients were current smokers.
  • The mean length of smoking cessation was 18.1 years.
  • Adenocarcinoma was more prevalent in never-smokers.

Takeaway

Even if people stop smoking, they can still get lung cancer many years later. This study looked at patients who had quit smoking and found many of them still developed lung cancer.

Methodology

Retrospective study analyzing lung cancer patients referred for surgery, examining smoking history and tumor histology.

Potential Biases

Potential underreporting of smoking history due to stigma.

Limitations

The study may not be generalizable due to selection bias and reliance on self-reported smoking history.

Participant Demographics

51.3% male, 48.7% female, mean age 70.1 years.

Statistical Information

P-Value

p = 0.0004

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1749-8090-6-19

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