Alcohol Consumption and Esophageal Health in Japanese Men
Author Information
Author(s): Akiyama Tomoyuki, Inamori Masahiko, Iida Hiroshi, Mawatari Hironori, Endo Hiroki, Hosono Kunihiro, Yoneda Kyoko, Fujita Koji, Yoneda Masato, Takahashi Hirokazu, Goto Ayumu, Abe Yasunobu, Kobayashi Noritoshi, Kubota Kensuke, Saito Satoru, Nakajima Atsushi
Primary Institution: Yokohama City University School of Medicine
Hypothesis
Is alcohol consumption associated with an increased risk of erosive esophagitis and Barrett's epithelium in Japanese men?
Conclusion
Alcohol consumption in Japanese men tends to be associated with an increased risk of erosive esophagitis and Barrett's epithelium.
Supporting Evidence
- 21.0% of the study population had erosive esophagitis.
- The prevalence of erosive esophagitis increased from 3% in the 1970s to 21.0% in 2006.
- Heavy drinkers had an odds ratio of 1.988 for erosive esophagitis compared to never drinkers.
Takeaway
Drinking alcohol can make your throat hurt and change the way it looks, especially in Japanese men.
Methodology
The study analyzed 463 men who underwent upper endoscopy, categorizing them based on their alcohol consumption levels and assessing the presence of erosive esophagitis and Barrett's epithelium.
Potential Biases
Potential bias due to self-reported data and exclusion of women.
Limitations
Self-reported alcohol consumption may lead to misclassification, and the study only included men, limiting generalizability.
Participant Demographics
463 male subjects, median age 67 years, age range 31-91 years.
Statistical Information
P-Value
p = 0.0190 for heavy drinkers and Barrett's epithelium
Confidence Interval
95% CI: 1.120 – 3.534 for heavy drinkers and erosive esophagitis
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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