Microbial Risk Factors of Cardiovascular and Cerebrovascular Diseases: Potential Therapeutical Options
2008

Microbial Risk Factors of Cardiovascular and Cerebrovascular Diseases

publication

Author Information

Author(s): Abdalla Abbas Mohammed, Guenther Albrecht, Galantucci Sebastiano, Fawi Gharib, Comi Giancarlo, Kwan Joseph, Corea Francesco

Primary Institution: Sohag Faculty of Medicine, Sohag University, Sohag, Egypt

Hypothesis

Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis.

Conclusion

Serum markers of Helicobacter pylori, Chlamydia pneumoniae, Cytomegalovirus, and odontopathogens may predict the risk of cardiovascular disease.

Supporting Evidence

  • Infections with organisms such as Helicobacter pylori and Chlamydia pneumoniae are potentially treatable emerging atherosclerotic risk factors.
  • Chronic infections can lead to a low-grade inflammatory response that may contribute to atherosclerosis.
  • Antibiotic therapy might improve the prognosis for patients with coronary heart disease.

Takeaway

Infections can make your heart sick, and doctors are looking for ways to treat these infections to help keep your heart healthy.

Limitations

The effects and cost implications of treatment strategies for microbial risk factors are largely unknown.

Digital Object Identifier (DOI)

10.2174/1874205X00802010020

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