Zangfu zheng (patterns) are associated with clinical manifestations of zang shang (target-organ damage) in arterial hypertension
2011

Zangfu Patterns and Target-Organ Damage in Hypertension

Sample size: 43 publication 10 minutes Evidence: moderate

Author Information

Author(s): Luiz Alexandre Bastos, Cordovil Ivan, Filho José Barbosa, Ferreira Arthur Sá

Primary Institution: National Institute of Cardiology, Brazil

Hypothesis

Patterns are associated with target-organ damage as manifestations indicate morbid conditions secondary to hypertension rather than simple blood pressure.

Conclusion

Zangfu patterns are associated with clinical manifestations of target-organ damage.

Supporting Evidence

  • The observed diagnostic accuracy was 98.0%, with sensitivity of 96.2% and specificity of 99.8%.
  • Twelve manifestations showed high prevalence, including red tongue (81.4%) and headache (72.1%).
  • Patterns were strongly or moderately associated with target-organ damage.

Takeaway

This study found that certain patterns in traditional Chinese medicine are linked to health problems caused by high blood pressure.

Methodology

A questionnaire was developed and applied to 43 subjects newly diagnosed with hypertension to analyze the association between Zangfu patterns and target-organ damage.

Potential Biases

Potential bias due to the predominance of certain patterns in the sample.

Limitations

The study did not explore silent target-organ damage in patients with hypertension.

Participant Demographics

43 subjects (26 female, 17 male) with a mean age of 54.1 years.

Statistical Information

P-Value

0.001

Confidence Interval

[97.3; 99.1]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1749-8546-6-23

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