The effect of leisure-time physical activity on the risk of acute myocardial infarction depending on Body Mass Index: a population-based case-control study
2006

Leisure-Time Physical Activity and Heart Attack Risk Based on BMI

Sample size: 4069 publication Evidence: moderate

Author Information

Author(s): Fransson Eleonor, de Faire Ulf, Ahlbom Anders, Reuterwall Christina, Hallqvist Johan, Alfredsson Lars

Primary Institution: Karolinska Institutet

Hypothesis

Does leisure-time physical activity reduce the risk of acute myocardial infarction differently among individuals with varying body mass index (BMI)?

Conclusion

Regular leisure-time physical activity reduces the risk of myocardial infarction in lean, normal-weight, and overweight individuals, but not in obese individuals.

Supporting Evidence

  • Regular physical activity was linked to a lower risk of heart attacks in normal-weight and overweight individuals.
  • Obese individuals who were active had a higher risk of heart attacks compared to normal-weight sedentary individuals.
  • The study included a large sample size of over 4000 participants.

Takeaway

Being active during your free time can help keep your heart healthy, especially if you're not overweight, but it might not help as much if you are obese.

Methodology

A population-based case-control study using data from the SHEEP study, involving questionnaires and clinical examinations to assess physical activity and BMI.

Potential Biases

Potential for selection bias due to varying response rates between fatal and non-fatal cases.

Limitations

Self-reported physical activity may lead to misclassification, and the study's design may not account for all confounding factors.

Participant Demographics

Participants included 1204 male and 550 female cases, and 1538 male and 777 female controls, aged 45-70 years.

Statistical Information

P-Value

0.05

Confidence Interval

95% CI 1.07–3.18

Statistical Significance

p=0.05

Digital Object Identifier (DOI)

10.1186/1471-2458-6-296

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