3-(2-Aminophenylsulfanyl)-1,3-diphenylpropan-1-one
2011
Study of a New Organic Compound
publication
Evidence: moderate
Author Information
Author(s): Yaeghoobi Marzieh, Khaledi Hamid, Abdullah Zanariah, Abd.Rahman Noorsaadah
Primary Institution: Department of Chemistry, University of Malaya, Kuala Lumpur, Malaysia
Hypothesis
The title compound is suggested to be an intermediate in the synthesis of benzothiazepines.
Conclusion
The compound features non-coplanar aromatic rings and specific molecular interactions that contribute to its crystal structure.
Supporting Evidence
- The compound has three aromatic rings that are not coplanar.
- Dihedral angles between the rings are measured at 84.75°, 88.01°, and 8.36°.
- N—H···π interactions link the molecules into chains along the b axis.
Takeaway
Scientists created a new chemical compound that has three rings not lying flat. This structure helps it connect with other molecules in a special way.
Methodology
The compound was synthesized by heating a mixture of chalcone, o-aminothiophenol, and ionic liquid, followed by extraction and recrystallization.
Digital Object Identifier (DOI)
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