Intensive Chemotherapy in Pancreatic Cancer
Author Information
Author(s): Cascinu S, Frontini L, Comella G, Barni S, Labianca R, Battelli N, Casaretti R, Zonato S, Pirovano M, Catalano G, Cellerino R
Primary Institution: Departments and Units of Medical Oncology, Ancona, Naples, Milan, Monza, Pesaro, Italy
Hypothesis
Is intensive weekly chemotherapy effective in advanced pancreatic cancer patients?
Conclusion
Intensive weekly chemotherapy is not effective in treating advanced pancreatic cancer patients.
Supporting Evidence
- Three partial responses were achieved for a response rate of 13%.
- Fifteen patients had a weight loss greater than 10%.
- Median survival of all patients was 6 months.
Takeaway
The study tested a strong chemotherapy treatment on people with advanced pancreatic cancer, but it didn't help most of them.
Methodology
Twenty-two patients received a specific chemotherapy regimen and were monitored for responses and side effects.
Limitations
The study had a small sample size and a short follow-up period.
Participant Demographics
Nineteen men and three women, median age 63 years.
Statistical Information
Confidence Interval
95% CI 0–26%
Digital Object Identifier (DOI)
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