Cytotoxic Effects of Bangladeshi Medicinal Plant Extracts
Author Information
Author(s): Uddin Shaikh J., Grice I. Darren, Tiralongo Evelin
Primary Institution: Griffith University
Hypothesis
To investigate the cytotoxic effect of some Bangladeshi medicinal plant extracts.
Conclusion
Some Bangladeshi medicinal plants showed selective cytotoxicity against cancer cells while being non-toxic to healthy cells.
Supporting Evidence
- The methanolic extract of Blumea lacera showed the highest cytotoxicity against all tested cell lines.
- Seven methanolic extracts showed low toxicity against mouse fibroblasts but selective cytotoxicity against different cancer cell lines.
- Some plant extracts showed low or no toxicity against healthy mouse fibroblasts, but selective cytotoxicity against breast cancer cells.
Takeaway
This study looked at 16 plants from Bangladesh to see if they could kill cancer cells without hurting healthy cells, and some did really well!
Methodology
The study involved extracting plant materials with various solvents and testing their cytotoxic effects on mouse fibroblasts and human cancer cell lines using the MTT assay.
Limitations
Limited research has been performed on these plants to evaluate their anticancer potential.
Digital Object Identifier (DOI)
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