Rosai-Dorfman Disease of the Orbit
Author Information
Author(s): Geeta K Vemuganti, Milind N Naik, Santosh G Honavar
Primary Institution: L V Prasad Eye Institute, Hyderabad, India
Hypothesis
To report the clinico-histopathologic features, management and outcome of Rosai-Dorfman disease of the orbit.
Conclusion
Rosai-Dorfman disease of the orbit, although rare, should be considered in young individuals with chronic proptosis with rubbery masses.
Supporting Evidence
- Rosai-Dorfman disease constituted 0.09% of all ocular specimens received at the Institute.
- Median duration of symptoms was 6 years (range 3–15 years).
- Two patients developed local recurrence that responded to systemic corticosteroid therapy.
Takeaway
Rosai-Dorfman disease is a rare condition that can cause swelling in the eye area, especially in young people, and can be treated with surgery and medication.
Methodology
We reviewed consecutive cases of orbital tumors on the registry of the Ophthalmic Pathology Service at a tertiary care centre between January 1996 and December 2002.
Limitations
The study is limited by its small sample size and retrospective design.
Participant Demographics
The median age was 13 years (range 5–65), with a male to female ratio of 3:4.
Digital Object Identifier (DOI)
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