From cat scratch disease to endocarditis, the possible natural history of Bartonella henselae infection
2007

From Cat Scratch Disease to Endocarditis: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Gouriet Frédérique, Lepidi Hubert, Habib Gilbert, Collart Frédéric, Raoult Didier

Primary Institution: Unité des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine, Université de la Méditerranée

Hypothesis

Does cat scratch disease represent the primary infection of Bartonella henselae that can lead to infective endocarditis in patients with heart valve lesions?

Conclusion

This case suggests that cat scratch disease may precede infective endocarditis in patients with pre-existing heart valve conditions.

Supporting Evidence

  • The patient had a history of cat scratch disease six months before developing endocarditis.
  • Histology revealed infective endocarditis with microorganisms consistent with Bartonella.
  • Serological testing showed an IgG titer of 1:200 against Bartonella antigens.

Takeaway

A man got sick from a cat scratch and later developed a serious heart infection. This shows that cat scratches can lead to heart problems in people who already have heart issues.

Methodology

The diagnosis was made through histology, culture, and serological evidence of Bartonella infection.

Limitations

The lymph node sample for PCR analysis to confirm cat scratch disease was not available.

Participant Demographics

A 43-year-old man with a history of heart valve issues.

Digital Object Identifier (DOI)

10.1186/1471-2334-7-30

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication