Reproductive Factors and Breast Cancer Risk in Young Women
Author Information
Author(s): H.-O. Adami, R. Bergström, E. Lund, O. Meirik
Primary Institution: University Hospital, Uppsala, Sweden
Hypothesis
Are reproductive variables associated with the risk of breast cancer in young women?
Conclusion
Reproductive factors did not explain the occurrence of breast cancer before the age of 45 in this population.
Supporting Evidence
- 422 cases and 527 controls were included in the study.
- Nulliparity was reported by 14% of patients and 14% of controls.
- Analysis revealed no significant association between parity and breast cancer.
- Breastfeeding for 24 months or more showed a relative risk of 0.5.
Takeaway
The study found that things like having children or breastfeeding don't really affect the chances of getting breast cancer for women under 45.
Methodology
A population-based case-control study was conducted with interviews of breast cancer patients and matched controls in Sweden and Norway.
Potential Biases
Potential biases could arise from the selection of controls and the reliance on self-reported data.
Limitations
The study may not have included all potential confounding factors and the sample size may limit the ability to detect weak associations.
Participant Demographics
Women under 45 years of age diagnosed with breast cancer and matched controls from the same population.
Statistical Information
P-Value
0.06
Confidence Interval
0.5-1.8
Statistical Significance
p=0.06
Want to read the original?
Access the complete publication on the publisher's website