Phase Change Material for Thermotherapy of Buruli Ulcer: A Prospective Observational Single Centre Proof-of-Principle Trial
2009

Using Heat to Treat Buruli Ulcer

Sample size: 6 publication Evidence: moderate

Author Information

Author(s): Junghanss Thomas, Um Boock Alphonse, Vogel Moritz, Schuette Daniela, Weinlaeder Helmut, Pluschke Gerd

Primary Institution: University Hospital, Heidelberg, Germany

Hypothesis

Is PCM-based heat application safe and effective for treating Buruli ulcer?

Conclusion

The PCM-based heat application device is effective and well-tolerated for treating Buruli ulcers.

Supporting Evidence

  • All patients completed the treatment successfully.
  • Patients with small ulcers healed completely without further intervention.
  • Patients with larger ulcers required skin grafting after heat treatment.
  • All patients were relapse-free 18 months after treatment.

Takeaway

Doctors used a special heat pack to help heal skin infections called Buruli ulcers, and it worked really well for the kids who tried it.

Methodology

A prospective observational trial where patients received heat treatment using PCM for 28-55 days.

Limitations

The study was conducted at a single center with a small sample size.

Participant Demographics

Patients aged 6 to 21 years with ulcerative Buruli lesions.

Digital Object Identifier (DOI)

10.1371/journal.pntd.0000380

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