DYNAMIC ASSOCIATIONS BETWEEN GLUCOSE AND ECOLOGICAL MOMENTARY COGNITION IN TYPE 1 DIABETES
2024

Glucose Fluctuations and Cognitive Performance in Type 1 Diabetes

Sample size: 200 publication Evidence: moderate

Author Information

Author(s): Hawks Zoe, Beck Emorie, Jung Lanee, Fonseca Luciana, Sliwinski Martin, Chaytor Naomi, Germine Laura

Primary Institution: McLean Hospital/Harvard Medical School

Hypothesis

How do naturally-occurring glucose fluctuations affect cognitive performance in adults with Type 1 Diabetes?

Conclusion

Minimizing glucose fluctuations is important for optimizing processing speed in individuals with Type 1 Diabetes.

Supporting Evidence

  • Cognitive variability is linked to fall risk and cognitive decline.
  • Large glucose fluctuations were associated with slower processing speed.
  • Some individuals showed greater cognitive vulnerability to glucose fluctuations.
  • Seven clinical characteristics predicted individual differences in cognitive vulnerability.

Takeaway

This study found that when people with Type 1 Diabetes have big changes in their blood sugar, it can make them think slower.

Methodology

The study used continuous glucose monitoring and cognitive ecological momentary assessment to analyze cognitive performance.

Participant Demographics

200 adults with Type 1 Diabetes.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2212

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