Excess Healthcare Costs and Resource Utilisation of Lyme Borreliosis in Germany: A Propensity Score–Matched Cohort Study
2024

Healthcare Costs of Lyme Disease in Germany

Sample size: 10690 publication 10 minutes Evidence: high

Author Information

Author(s): Gordon Brestrich, Joanna Diesing, Nils Kossack, James H. Stark, Andreas Pilz, Holly Yu, Jochen Suess

Primary Institution: Pfizer Pharma GmbH

Hypothesis

What are the healthcare costs and resource utilization associated with Lyme borreliosis in Germany?

Conclusion

The study shows that Lyme borreliosis imposes a substantial economic burden on the German healthcare system.

Supporting Evidence

  • Patients with disseminated Lyme disease incurred significantly higher healthcare costs compared to controls.
  • Lyme borreliosis was associated with €64.5 million in excess costs for the German healthcare system.
  • Disseminated manifestations accounted for 66% of the overall excess costs despite being only 7.8% of all cases.

Takeaway

Lyme disease costs a lot of money for doctors and hospitals in Germany, especially for people with serious cases.

Methodology

The study used claims data from a database to identify patients with Lyme disease and matched them with control patients to assess healthcare costs and resource utilization over three years.

Potential Biases

Potential coding inaccuracies could lead to misclassification of Lyme disease cases.

Limitations

The study may have residual confounding due to unmeasured variables and did not include indirect costs.

Participant Demographics

Patients of all ages with statutory health insurance in Germany were included.

Statistical Information

P-Value

0.001

Confidence Interval

95% CI: 53.5–75.6 million

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1111/zph.13180

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