Syphilis Infection Prevalence in the Middle East and North Africa
Author Information
Author(s): El-Jamal Mariam, Annan Beyhan, Al Tawil Alaa, Hamati Melissa, Almukdad Sawsan, Fakih Iman, Dabdoub Fatema, Sharara Eman, Jamil Muhammad S., Alaama Ahmed S., Hermez Joumana G., Rowley Jane, Abu-Raddad Laith J., Mumtaz Ghina R.
Primary Institution: American University of Beirut, Beirut, Lebanon
Hypothesis
What is the prevalence of syphilis infection in the Middle East and North Africa region?
Conclusion
Syphilis prevalence in MENA is comparable to global levels, indicating a significant disease burden that requires urgent public health action.
Supporting Evidence
- The pooled prevalence for probable current syphilis infection was 0.004% among blood donors and 0.48% in the general population.
- 12.58% prevalence was found among female sex workers.
- 22.52% prevalence was found among men who have sex with men and transgender people.
- Meta-regression analyses explained 62% of the prevalence variation.
- An annual decline of 3% in prevalence among general population groups was observed.
Takeaway
Syphilis is a common infection in the Middle East and North Africa, affecting many people, especially those at higher risk, like sex workers and men who have sex with men.
Methodology
A systematic review and meta-analysis were conducted, assessing syphilis prevalence across 24 MENA countries using data from 643 studies.
Potential Biases
Potential overestimation of prevalence due to convenience sampling and underreporting in stigmatized populations.
Limitations
Variability in data availability across countries and population groups, potential biases in sampling methods, and limited recent data for certain populations.
Participant Demographics
The study included diverse populations across 24 MENA countries, with a focus on high-risk groups such as men who have sex with men and female sex workers.
Statistical Information
Confidence Interval
95% CI: 0.001%–34.06%
Digital Object Identifier (DOI)
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