High risk mammographic parenchymal patterns and diet: a case–control study
2000

Diet and Mammographic Patterns in Breast Cancer Risk

Sample size: 400 publication Evidence: moderate

Author Information

Author(s): E Sala, R Warren, S Duffy, A Welch, R Luben, N Day

Primary Institution: Department of Public Health and Primary Care, Strangeways Research Laboratory

Hypothesis

Mammographic parenchymal patterns are related to breast cancer risk and are affected by diet.

Conclusion

Certain macronutrients and foods, like protein, carbohydrates, and meat, influence breast cancer risk through their effects on breast tissue morphology.

Supporting Evidence

  • The adjusted odds ratio of having a high-risk pattern in women with high protein intake was 2.00.
  • The adjusted odds ratio of having a high-risk pattern in women with high carbohydrate intake was 1.93.
  • Total meat intake was associated with high-risk patterns among post-menopausal women with an OR of 2.50.

Takeaway

Eating certain foods like protein and meat can change how breast tissue looks on mammograms, which might help show breast cancer risk.

Methodology

A case–control study with 200 high-risk and 200 low-risk women, evaluating mammograms and dietary intake.

Participant Demographics

Women with high-risk and low-risk mammographic patterns.

Statistical Information

P-Value

0.04

Confidence Interval

95% CI 1.06–3.77

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1054/bjoc.2000.1151

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