New Fibrinogen Standard for Blood Testing
Author Information
Author(s): Masahiro Okuda, Yahiro Uemura, Noriyuki Tatsumi, Susumu Honda
Primary Institution: Sysmex Corporation
Hypothesis
Can a new fibrinogen standard improve the accuracy and precision of plasma fibrinogen measurement in clinical laboratories?
Conclusion
The newly developed fibrinogen standard shows high precision and stability, making it suitable for use in Japanese clinical laboratories.
Supporting Evidence
- The new fibrinogen standard showed a coefficient of variation of 1.4-2.1%, indicating excellent precision.
- The within-analyser variability among five instruments was consistent with a mean of 2.20 g l-1.
- The degradation study suggested that the standard could be stored at 9°C for two years without significant loss.
Takeaway
Scientists created a new standard for measuring fibrinogen in blood that works better than the old ones, helping doctors get more accurate results.
Methodology
The study involved preparing a fibrinogen standard from human plasma and testing its performance across various coagulation analysers.
Limitations
The study primarily focuses on the Japanese context and may not be applicable globally.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website