The postmastectomy pain syndrome: an epidemiological study on the prevalence of chronic pain after surgery for breast cancer
2008

Postmastectomy Pain Syndrome Study

Sample size: 258 publication Evidence: moderate

Author Information

Author(s): Vilholm O J, Cold S, Rasmussen L, Sindrup S H

Primary Institution: Odense University Hospital

Hypothesis

What is the prevalence of chronic pain after surgery for breast cancer?

Conclusion

The study found that 23.9% of breast cancer patients experience postmastectomy pain syndrome (PMPS) after surgery.

Supporting Evidence

  • The prevalence of PMPS was found to be 23.9%.
  • The odds ratio for developing PMPS was 2.88.
  • Significant risk factors included previous breast surgery, tumor location, and young age.

Takeaway

After breast cancer surgery, some women can have pain that lasts a long time, and this study found that about 1 in 4 women experience this pain.

Methodology

A postal survey was conducted among breast cancer patients and a reference group, assessing pain prevalence and characteristics through questionnaires.

Potential Biases

Potential bias due to including women with possible reoccurrence of cancer, which may have influenced pain reports.

Limitations

The study was limited to one center and included only Caucasian women, which may affect the generalizability of the results.

Participant Demographics

The study included women who underwent surgery for breast cancer, with a median age of 61.1 years.

Statistical Information

P-Value

0.003

Confidence Interval

95% CI 1.84–4.51

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604534

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