Three years follow-up of screen-detected diabetic and non-diabetic subjects: who is better off? The ADDITION Netherlands study
2008

Follow-up Study of Diabetic and Non-Diabetic Patients

Sample size: 354 publication Evidence: moderate

Author Information

Author(s): Janssen Paul GH, Gorter Kees J, Stolk Ronald P, Akarsubasi Mehmet, Rutten Guy EHM

Primary Institution: University Medical Center, Utrecht, the Netherlands

Hypothesis

What is the extent of health care utilization and cardiovascular risk in non-diabetic individuals with an elevated risk score compared to diabetic patients?

Conclusion

Screened non-diabetic participants with an elevated risk score had cardiovascular event rates comparable to those of diabetic patients after three years.

Supporting Evidence

  • Participants with IGT had the highest progression rate to diabetes.
  • Cardiovascular medication use increased in all categories, most significantly in diabetic patients.
  • Diabetic patients had more frequent healthcare encounters compared to non-diabetic participants.

Takeaway

This study shows that people who are at risk for heart problems but don't have diabetes might not be getting the care they need, while those with diabetes are getting better treatment.

Methodology

Participants were screened for diabetes and categorized based on glucose tolerance, with follow-up data collected on medication use and cardiovascular events over three years.

Potential Biases

Data collection was not blinded, which could introduce bias, although it was derived from computerized patient records.

Limitations

The study excluded diabetic patients treated intensively in the intervention arm, lacked sufficient data for non-diabetic participants' lipid levels, and had a small sample size which may affect the significance of results.

Participant Demographics

Participants were predominantly Caucasian, aged 50-70 years.

Statistical Information

P-Value

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2296-9-67

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