Thyroid Cancer Burden in China and Worldwide (1990-2021)
Author Information
Author(s): Meng Ziang, Pan Ti, Yu Jingjing, Shi Chao, Liu Xuxu, Xue Dongbo, Wang Jing, Ma Biao
Primary Institution: The First Affiliated Hospital of Harbin Medical University, Harbin, China
Hypothesis
The study aims to analyze the incidence, prevalence, death, and disability-adjusted life years of thyroid cancer in China and worldwide from 1990 to 2021.
Conclusion
Thyroid cancer remains a significant public health challenge in China, with increasing incidence and prevalence rates, necessitating careful management of screening and treatment.
Supporting Evidence
- The incidence and prevalence rates of thyroid cancer in China have been consistently rising since 1990.
- Thyroid cancer is projected to become the fourth most prevalent cancer worldwide.
- Females account for the majority of the thyroid cancer burden, although the incidence in males is increasing faster.
Takeaway
Thyroid cancer is becoming more common, especially in China, and we need to be careful about how we screen and treat it to avoid unnecessary procedures.
Methodology
The study utilized the Global Burden of Disease Study 2021 database to assess thyroid cancer metrics using statistical models including Joinpoint regression and ARIMA.
Potential Biases
Potential overestimation of prevalence due to reliance on cross-sectional studies and the absence of cancer-specific death rates.
Limitations
The study relies on publicly available data, which may introduce uncertainty, and lacks detailed pathological data for various thyroid cancer subtypes.
Participant Demographics
The study indicates that thyroid cancer is more prevalent in women than men, with a significant burden among middle-aged and elderly populations.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI: 1.249 (1.009-1.473) to 2.473 (1.993-3.088)
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website