N-Cyclohexyl-2-(5-fluoro-1H-indol-3-yl)-2-oxoacetamide
2011
Crystal Structure of N-Cyclohexyl-2-(5-fluoro-1H-indol-3-yl)-2-oxoacetamide
publication
Evidence: moderate
Author Information
Author(s): Tian Dan-Li, Luo Gang, Chen Hong, Tang Xiao-Wei, Liu Yong-Feng
Primary Institution: School of Pharmacy, Tianjin Medical University
Conclusion
The study successfully determined the crystal structure of the compound, revealing its stable conformation and intermolecular interactions.
Supporting Evidence
- The cyclohexane ring adopts a chair conformation.
- Crystal packing is stabilized by weak π–π stacking interactions.
- Intermolecular hydrogen-bond interactions contribute to the stability of the structure.
Takeaway
The researchers looked at a new chemical compound and found out how its atoms are arranged in a solid form.
Methodology
The compound was synthesized in two steps and analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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