NMRDyn: A Program for Analyzing Protein Self-Association
Author Information
Author(s): Conan K. Wang, Horst Joachim Schirra, David J. Craik
Primary Institution: The University of Queensland, Institute for Molecular Bioscience, Brisbane, Queensland, Australia
Hypothesis
NMR relaxation measurements can provide detailed information about protein self-association.
Conclusion
NMRdyn is an effective tool for analyzing NMR relaxation data and studying protein self-association.
Supporting Evidence
- NMRdyn can handle multiple sets of NMR relaxation data at different protein concentrations.
- The program features a user-friendly interface to facilitate data analysis.
- NMRdyn was validated by comparing its results with those from another program, relax.
Takeaway
NMRdyn is a computer program that helps scientists understand how proteins stick together by analyzing special data from NMR experiments.
Methodology
NMRdyn analyzes NMR relaxation data to optimize parameters describing protein dynamics and self-association.
Limitations
NMRdyn is not suitable for C=O relaxation data, which can be complicated by chemical shift anisotropy.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website