Multimodal Exercises for Chemotherapy-Induced Peripheral Neuropathy
Author Information
Author(s): Muacevic Alexander, Adler John R, Yadav Trupti, Varadharajulu G., Gudur Rashmi
Primary Institution: Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND
Hypothesis
Does a multimodal exercise program reduce symptoms of chemotherapy-induced peripheral neuropathy (CIPN) compared to standard physical therapy?
Conclusion
The multimodal exercise program is more effective in reducing CIPN symptoms and improving daily living skills than standard physical therapy.
Supporting Evidence
- Group A showed a significant reduction in neuropathy symptoms with a mean mTNS score decrease from 14.68 to 7.03.
- Group A's L-IADL scores improved significantly from 7.54 to 11.23.
- Statistical analysis indicated a p-value of <0.0001 for both outcome measures in Group A.
Takeaway
Doing different types of exercises can help people feel better after chemotherapy and make it easier for them to do everyday tasks.
Methodology
Participants were divided into two groups: one received a multimodal exercise program while the other received standard physical therapy, with assessments before and after the intervention.
Potential Biases
The study may have bias due to the non-randomized design and potential differences in participant characteristics.
Limitations
The study was limited to a specific age range and type of chemotherapy, which may affect generalizability.
Participant Demographics
Participants were aged 25-55 years with chemotherapy-induced peripheral neuropathy.
Statistical Information
P-Value
<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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