Case Report on Treating Adrenomyeloneuropathy with Lorenzo's Oil and DHA
Author Information
Author(s): Terre'Blanche Gisella, van der Walt Mietha M, Bergh Jacobus J, Mienie Lodewyk J
Primary Institution: North-West University
Hypothesis
Can supplementation with docosahexaenoic acid (DHA) in addition to Lorenzo's oil improve clinical symptoms and increase DHA levels in a patient with adrenomyeloneuropathy?
Conclusion
Supplementation with DHA, alongside Lorenzo's oil and atorvastatin, increased DHA levels in the patient but did not improve neurological symptoms.
Supporting Evidence
- Atorvastatin and L-carnitine treatment reduced VLCFA plasma levels initially.
- Lorenzo's oil treatment decreased VLCFA ratios but failed to sustain improvements.
- DHA supplementation increased DHA levels in plasma and red blood cells.
Takeaway
The study looked at one patient with a rare disease and found that adding a special oil didn't help them feel better, but it did increase some important fats in their blood.
Methodology
The patient was treated with atorvastatin, Lorenzo's oil, and DHA, with evaluations through MRI and blood tests over several months.
Limitations
The study is based on a single case, limiting the generalizability of the findings.
Participant Demographics
A 34-year-old male patient diagnosed with adrenomyeloneuropathy.
Digital Object Identifier (DOI)
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