Endobronchial Ultrasonography to Assess and Evaluate Tracheobronchial Tree Invasion in cT4b Esophageal Cancer Patients Treated with Definitive Chemoradiotherapy: Assessment of Resectability
2024

Using Endobronchial Ultrasound to Check for Cancer Spread in Esophageal Patients

Sample size: 26 publication Evidence: moderate

Author Information

Author(s): Defize I. L., de Groot E. M., van de Langerijt O., van Velzen M., Mook S., Haj Mohammad N., Bulbul M., Ruurda J. P., van Hillegersberg R.

Primary Institution: University Medical Center Utrecht

Hypothesis

Can endobronchial ultrasound accurately assess tracheobronchial tree invasion in cT4b esophageal cancer patients after definitive chemoradiotherapy?

Conclusion

Endobronchial ultrasound is effective in assessing tracheobronchial tree invasion in cT4b esophageal cancer patients after treatment, aiding in patient selection for surgery.

Supporting Evidence

  • 90% of patients without tracheobronchial invasion achieved radical resection.
  • The study included 26 patients who underwent endobronchial ultrasound.
  • Persistent ingrowth was observed in six patients, with follow-up evaluations showing changes in tumor status.

Takeaway

Doctors used a special ultrasound to see if cancer had spread in patients' airways after treatment, helping them decide who could safely have surgery.

Methodology

Patients with suspected tracheobronchial invasion underwent endobronchial ultrasound and were evaluated for surgery based on the results.

Potential Biases

Inter- and intra-observer variability in EBUS interpretation may affect results.

Limitations

The study's retrospective nature and the exclusion of patients with persistent ingrowth limit the generalizability of the findings.

Participant Demographics

{"total":26,"sex_distribution":{"male":19,"female":7},"mean_age":64,"mean_bmi":23,"asa_classification":{"1":1,"2":19,"3":6}}

Digital Object Identifier (DOI)

10.1245/s10434-024-15621-1

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