Assessing Visual Function in Geographic Atrophy Lesions
Author Information
Author(s): Alibhai A. Yasin, Moult Eric, Jamil Muhammad Usman, Raza Khadija, Morales Marco U., Ribiero Ramiro, Baumal Caroline R., Fujimoto James G., Waheed Nadia K.
Hypothesis
To assess the repeatability of a microperimetry methodology for quantifying visual function changes in the junctional zone of eyes with geographic atrophy.
Conclusion
The methodology is reliable and suitable for analyzing retinal sensitivity in high-risk areas.
Supporting Evidence
- The intraclass correlation for mean junctional zone sensitivity was 0.994.
- The coefficient of repeatability for mean junctional zone sensitivity was 0.349 dB.
- The intraclass correlation for the total number of scotomatous points was 0.997.
- The coefficient of repeatability for the total number of scotomatous points was 0.218.
Takeaway
This study checks if a new eye test can give consistent results when looking at specific areas in the eyes of people with a certain eye disease.
Methodology
A post hoc analysis of the OAKS phase III trial was conducted, involving microperimetry assessments and FAF image registrations.
Participant Demographics
Patients with geographic atrophy secondary to age-related macular degeneration.
Digital Object Identifier (DOI)
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