Clinico-pathological and treatment-related factors influencing survival in parotid cancer
1999

Factors Affecting Survival in Parotid Cancer

Sample size: 103 publication Evidence: high

Author Information

Author(s): Renehan A G, Gleave E N, Slevin N J, McGurk M

Primary Institution: Christie Hospital NHS Trust, Manchester, UK

Hypothesis

What are the prognostic and treatment-related factors that influence survival in patients with parotid cancer?

Conclusion

Tumour characteristics, particularly clinical stage and grade, primarily determine long-term survival in parotid cancer patients.

Supporting Evidence

  • The 10-year disease-specific survival rates for stage I, II and III/IV were 96%, 61% and 17% respectively.
  • Histological types showed 10-year survival rates of 93%, 41%, and 50% for low-, intermediate-, and high-grade tumours respectively.
  • Tumour size greater than 4 cm significantly increased the risk of cancer death.

Takeaway

This study looked at patients with parotid cancer and found that how big the tumor is and its type are really important for survival.

Methodology

Analysis of 103 patients treated surgically for primary parotid cancer to assess survival factors.

Participant Demographics

Patients with primary parotid cancer treated at Christie Hospital, Manchester from 1952 to 1992.

Statistical Information

P-Value

P < 0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1038/sj.bjc.6990501

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