Congenital scoliosis in monozygotic twins: case report and review of possible factors contributing to its development
2008

Congenital Scoliosis in Monozygotic Twins

Sample size: 2 publication Evidence: low

Author Information

Author(s): Kaspiris Angelos, Grivas Theodoros B, Weiss Hans-Rudolf

Primary Institution: Department of Trauma and Orthopaedics, 'Thriasio' General Hospital

Hypothesis

The study aims to report a case of congenital scoliosis in monozygotic twins and review the literature on similar cases and contributing factors.

Conclusion

Both genetic and environmental factors seem to play a significant role in the development of congenital scoliosis.

Supporting Evidence

  • Congenital scoliosis was diagnosed in both twins at the age of 11.
  • The first twin had a Cobb angle of 34 degrees, while the second had a Cobb angle of 10 degrees.
  • Both twins exhibited moderate mental retardation and dyslalia.

Takeaway

This study looks at two identical twins who both have scoliosis, showing that even identical genes can lead to different health issues due to other factors.

Methodology

Clinical examination and simple X-rays were used to assess the twins' scoliosis.

Limitations

The study is based on a single case report, limiting the generalizability of the findings.

Participant Demographics

Two male monozygotic twins, born in May 1992.

Digital Object Identifier (DOI)

10.1186/1748-7161-3-17

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