4-[(3-Benzamidomethyl-6-phenyl-6,7-dihydro-5H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazin-7-yl)carbonyl]-3-phenyl-1,2,3-oxadiazol-3-ium-5-olate 0.06-hydrate
2011
Study of a New Organic Compound with Biological Potential
publication
Evidence: moderate
Author Information
Author(s): Fun Hoong-Kun, Hemamalini Madhukar, Nithinchandra Kalluraya Balakrishna
Primary Institution: Universiti Sains Malaysia
Hypothesis
The introduction of a triazolothiadiazole moiety at the 4-position of phenylsydnone will yield compounds with enhanced biological activity.
Conclusion
The crystal structure of the compound reveals a three-dimensional network formed by various hydrogen bonds.
Supporting Evidence
- The compound contains four syndone molecules and a water molecule.
- The dihedral angles between terminal phenyl rings vary significantly.
- The crystal structure is stabilized by multiple hydrogen bonds.
Takeaway
Scientists created a new chemical compound and studied its structure to see how it might be useful in medicine.
Methodology
The compound was synthesized through a reaction involving specific chemical precursors and characterized using X-ray crystallography.
Digital Object Identifier (DOI)
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